Biopharmaceutics

Biopharmaceutics is defined as the study of factors
influencing the rate and amount of drug that reaches the systemic circulation
and use of this information to optimize the therapeutic efficacy of the drug
products.

Absorption

The process of movement of the drug from its site
of administration to the systemic circulation is called as absorption. .......

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Bioavailability

Bioavailability is defined as the rate and extend
(amount) of the drug absorption.

Distribution

The movement of drug between one compartment and
the other (generally blood and the extravascular tissues) is referred to as drug
distribution.

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Elimination

Elimination is defined as the process that tends to
remove the drug from the body and terminate its action.

Elimination occurs by 2 process –

Biotransformation (metabolism)

Excreation

Pharmacokinetics

Its defined as the study of time
course of drug ADME and their relationship with its therapeutic and toxic
effects of the drug